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beast
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Indonesian girl contracted by bird flu
« Feb 13, 2008    12:17:21 AM »
 Indonesian girl contracted by bird flu

    JAKARTA, Feb. 12 (Xinhua) -- A 15-year-old Indonesian girl from West Jakarta has been infected by avian influenza, bringing the total cases to 127 with 103 of them fatal, Indonesian health ministry said here Tuesday.

    The girl was a daughter of a 38-year-old woman who was previously infected by the disease and first developed the symptoms of the disease on Jan. 23, said the spokeswoman of the ministry Lily Sriwahyuni Sulistyowati.

    The girl was now in critical condition at a hospital, said Sulistyowati.

    "Both of her laboratory tests showed today that the girl is positive on bird flu," she told Xinhua.

    She said that it was not clear yet whether the girl had historical contacts with fowls.

    "Investigations into the source of her infection are ongoing. However, she was exposed to her sick mother on Jan. 27-28 and spent time in a neighborhood where chickens and other birds were found," said Sulistyowati.

    "Samples from these birds have been taken and are undergoing tests to determine whether they may have been the source of infection," she said.

    Contact with fowls has been the common source of the infection of the disease in Indonesia.

    The spokesperson said that the girl first showed the symptoms of the H5N1 virus on Feb. 2 and was hospitalized on Feb. 8.

    Experts have said that improper initial medical treatment and poor hygiene of the traditional poultry market have been blamed for the highest fatality rate of bird flu in Indonesia, the world's fourth most populous country with a population of over 240 million.

    Indonesia has been grappled with major problem on its effort to stop the spread of the virus spread, including huge territory, traditional way of rising chickens on back yard and lack of obedience of provincial administration in implementing the Jakarta decision to stop the virus spread.


Source: http://news.xinhuanet.com/english/2008-02/13/content_7594244.htm
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beast
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Re: Indonesian girl contracted by bird flu
« Feb 13, 2008    01:29:49 AM »
Likely Human to Human H5N1 Transmission in Jakarta Cluster

Recombinomics Commentary 14:38
February 12, 2008

A 15-year-old female from West Jakarta, Jakarta Province developed symptoms on 2 February, was hospitalized on 8 February and is currently in hospital in a critical condition. The case is the daughter of a previously confirmed case, the 38-year-old female from West Jakarta, Jakarta Province who developed symptoms on 23 January.

Investigations into the source of her infection are ongoing. However, she was exposed to her sick mother on 27-28 January and spent time in a neighbourbood where chickens and other birds were found.

The above comments from the WHO update describe a confirmed cluster in West Jakarta.  The gap in the disease onset dates, as well as the timing of the exposure indicates this is a case of human to human transmission.  Although H5N1 infections of humans have been high in Indonesia, and highest in the Jakarta area, the likelihood to two family members being independently infected is remote.  However, the likelihood of transmission within a family is high, because of close contact that is common between family members.

The “exposure” of the 15F to her 38F mother probably involved visits to her mother, who was hospitalized on January 26 in Tangerang and was subsequently transfered and was in critical condition.

In this instance, sequencing of H5N1 from the two patients would be useful.


Source: http://www.recombinomics.com/News/02120801/H5N1_W_Jakarta_H2H.html
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